Analysis of the Effect of Blood Sugar, Calcium, Chloride Ions, and Blood Urea Nitrogen on Skin Wrink
Analysis of the Effect of Blood Sugar, Calcium, Chloride Ions, and Blood Urea Nitrogen on Skin Wrinkles
Purpose : The purpose of this study was to statistically verify the effects of blood glucose, blood urea nitrogen (BUN), calcium, and chloride ions on the facial wrinkles of premenopausal women.
Methods : Premenopausal women were recruited through the internet to be study participants. Those who had disease or who consumed drugs or health foods such as ginseng were excluded. The levels of blood glucose, BUN, calcium, and chloride ions were obtained, and facial wrinkles were measured with a skin meter. Multiple regression analysis was performed to evaluate the effects of blood glucose, BUN, calcium, and chloride ions on face wrinkles.
Results : After excluding 13 people whose blood measurement variables deviated from the outliers, statistical analysis was performed for the remaining 64 participants. Analysis revealed the nonstandardization coefficient of blood glucose to be 0.019 and the significance probability was p=0.027. The nonstandardized coefficient of BUN was 0.108, and the significance probability was p=0.006, which means that when BUN increased by 1 mg/dL, wrinkles increased by 0.108. The explanatory power of R2 was 0.203.
Conclusion : This is the first report to reveal, based on empirical data, that blood glucose and BUN, which are known factors affecting cardiovascular disease and diabetes, also affect facial wrinkles.